This note grew from the lectures I delivered at ICTP during the Summer School in honor of Hochster and Huneke. Its purpose is to provide an introduction to the notion of equimultiplicity (of numerical invariants of singularities/local rings) and survey past work on equimultiplicity of Hilbert-Kunz multiplicity and F-signature. The treatment of F-signature is from joint work with Thomas Polstra and the section on Hilbert-Kunz multiplicity updates my previous paper on the topic and gives novel applications.